CD38 / DyLight 633 /
Product Details
Description | The monoclonal antibody is directed against the CD38-antigen, which is strongly expressed plasma cell. The CD 38-antigen is expressed at variable levels on the majority of hemopoietic cells, prevalently during early differentiation and activation. | |
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Conjugate | DyLight 633 | |
Clone | ||
Target Species | Human | |
Applications | FC | |
Supplier | Abbexa | |
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About CD38
The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
About DyLight 633
DyLight™ 633 is a red-emitting fluroescent dye that can be excited by the 628 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 633 has an excitation peak of 638 nm and an emission peak of 658 nm, and is spectrally similar to Alexa Fluor™ 633. DyLight™ 633 is most commonly used in flow cytometery and fluorescence microscopy applications.
DyLight™ 633 is a red-emitting fluroescent dye that can be excited by the 628 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 633 has an excitation peak of 638 nm and an emission peak of 658 nm, and is spectrally similar to Alexa Fluor™ 633. DyLight™ 633 is most commonly used in flow cytometery and fluorescence microscopy applications.
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2287 CD38 antibodies from over 54 suppliers available with over 162 conjugates.