CD11a / OC515 /
Product Details
| Description | The monoclonal antibody is directed against the CD11a- antigen, located on the alpha-L chain of LFA-1 complex (Lymphocyte Function-associated Antigen-1), which is expressed on mature immunocompetent lymphocytes and their neoplastic counterparts, granulocytes and monocytes. | |
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| Conjugate | OC515 | |
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| Target Species | Human | |
| Applications | FC | |
| Supplier | Abbexa | |
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About CD11a
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
About OC515
OC515, also known as Orange Cytognos 515, is an orange fluorescent dye similar to Pacific Orange.
OC515, also known as Orange Cytognos 515, is an orange fluorescent dye similar to Pacific Orange.
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1755 CD11a antibodies from over 48 suppliers available with over 73 conjugates.
