TCR V beta 6 Monoclonal / PE / REA884

Product Details

Description	Clone REA884 recognizes the mouse V beta 6 T cell receptor (TCR Vbeta6). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules and plays an important role in T cell mediated immune responses. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. The alpha and beta TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. REA884 recognizes TCR Vbeta6 on mouse strains with the a (e.g., C57BR and SJL) and b haplotypes (e.g., BALB/c, C3H, and DBA/1). \| Additional information: Clone REA884 displays negligible binding to Fc receptors.
Conjugate	PE
Clone	REA884
Target Species	Mouse
Applications	FC
Supplier	Miltenyi Biotec
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About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

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