TCR V beta 6 Monoclonal / APC-Vio770 / REA884

Product Details
Description Clone REA884 recognizes the mouse V beta 6 T cell receptor (TCR Vbeta6). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules and plays an important role in T cell mediated immune responses. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. The alpha and beta TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. REA884 recognizes TCR Vbeta6 on mouse strains with the a (e.g., C57BR and SJL) and b haplotypes (e.g., BALB/c, C3H, and DBA/1). | Additional information: Clone REA884 displays negligible binding to Fc receptors.
Conjugate APC-Vio770
Clone REA884
Target Species Mouse
Applications FC
Supplier Miltenyi Biotec
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About APC-Vio770
APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.
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Validation References
PMID 1316931
PMID 2531186
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39 TCR V beta 6 antibodies from over 5 suppliers available with over 26 conjugates.

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