TCR V beta 12 Monoclonal / PE-Vio770 / REA946

Product Details

Description	Clone REA946 recognizes the mouse V beta 12 T cell receptor (TCR Vbeta12). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules and plays an important role in T cell mediated immune responses. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. The alpha and beta TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. REA946 recognizes TCR Vbeta12 on mouse strains with b haplotypes (e.g., BALB/c, C3H, and DBA/1). \| Additional information: Clone REA946 displays negligible binding to Fc receptors.
Conjugate	PE-Vio770
Clone	REA946
Target Species	Mouse
Applications	FC
Supplier	Miltenyi Biotec
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About PE-Vio770
PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.

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