TCR V beta 12 Monoclonal / APC-Vio770 / REA946

Product Details

Description	Clone REA946 recognizes the mouse V beta 12 T cell receptor (TCR Vbeta12). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules and plays an important role in T cell mediated immune responses. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. The alpha and beta TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. REA946 recognizes TCR Vbeta12 on mouse strains with b haplotypes (e.g., BALB/c, C3H, and DBA/1). \| Additional information: Clone REA946 displays negligible binding to Fc receptors.
Conjugate	APC-Vio770
Clone	REA946
Target Species	Mouse
Applications	FC
Supplier	Miltenyi Biotec
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About APC-Vio770
APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.

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