CD133 epitope 2 Monoclonal / PE-Vio770 / 293C3

Product Details
Description CD133 is a novel 5-transmembrane cell surface antigen with a molecular weight of 117 kDa. CD133/2 (293C3) antibodies recognize epitope 2 of the human CD133 antigen (CD133/2). In the hematopoietic system, CD133 expression is restricted to a subset of CD34bright stem and progenitor cells in human fetal liver, bone marrow, cord blood, and peripheral blood. Additionally, CD133 is expressed by a small portion of CD34– cells in these tissues. The CD34+CD133+ cell population, which includes CD34+CD38– cells, was shown to be capable of repopulating NOD/SCID mice. Recently, CD133 has also been found to be expressed on circulating endothelial progenitor cells, tissue-specific stem cells, cancer stem cells from tumor tissues, fetal neural stem cells, and ES and iPS cell–derived cells as well as on other tissue-specific stem cells, such as renal, prostate, and corneal stem cells. The putative murine homologue, prominin, which is expressed on neuroepithelial and epithelial mouse cells, was dentified.
Conjugate PE-Vio770
Clone 293C3
Target Species Human
Applications FC
Supplier Miltenyi Biotec
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About PE-Vio770
PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.
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119 CD133 epitope 2 antibodies from over 12 suppliers available with over 13 conjugates.

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