CD66a/c/e Monoclonal / PE / REA889

Product Details

Description	Clone REA889 recognizes the a, c, and e epitopes of the human CD66 antigen. CD66 constitutes a gene family whose members belong to the Ig superfamily of carcinoembryonic antigens (CEA). They are involved in a wide variety of physiological processes such as embryonic development, pregnancy, bile transport, as well as pathological conditions such as cancer, bacterial or viral infection, and inflammation. CD66a (CEACAM1), CD66c (CEACAM6), and CD66e (CEACAM5) are differentially expressed on some epithelial cells as well as on T cells, NK cell subsets, and granulocytes, especially neutrophils. \| Additional information: Clone REA889 displays negligible binding to Fc receptors.
Conjugate	PE
Clone	REA889
Target Species	Human
Applications	FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Supplier	Miltenyi Biotec
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About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

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