CD33 / PE /

Product Details
Description The antigen is a single chain transmembrane glycoprotein of molecular mass 67 kDa expressed on monocytes, myeloid progenitor cells and myeloid leukaemias. The antigen has homology with CD22 and myelin associated glycoprotein. CD33 appears very early on myelomonocytic precursors and is expressed in both the myeloid and monocytic cell lineages. CD33 is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages
Conjugate PE
Clone
Target Species Human, Monkey
Applications FC
Supplier Abbexa
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About CD33
Enables protein phosphatase binding activity and sialic acid binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine phosphatase activity. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome. [provided by Alliance of Genome Resources, Apr 2022]
About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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1812 CD33 antibodies from over 50 suppliers available with over 146 conjugates.

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