CD36 Monoclonal / VioGreen / REA760
Product Details
Description | Clone REA760 recognizes the human CD36 antigen, an integral membrane protein, which is a member of the class B scavenger receptor family of cell surface proteins. CD36 is expressed on various epithelial and endothelial cells as well as erythrocytes, platelets, monocytes, and macrophages, and some macrophage-derived dendritic cells. CD36 functions as a scavenger receptor for long chain fatty acids, oxidized LDL, collagen type I, IV, and V, and thrombospondin, as well as for apoptotic cells. CD36 is an early marker of erythroid differentiation. | Additional information: Clone REA760 displays negligible binding to Fc receptors. | |
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Conjugate | VioGreen | |
Clone | REA760 | |
Target Species | Human | |
Applications | FC | |
Supplier | Miltenyi Biotec | |
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About CD36
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]
About VioGreen
Vio®Green from Miltenyi has an excitation peak at 388 nm and an emission peak at 520 nm.
Vio®Green from Miltenyi has an excitation peak at 388 nm and an emission peak at 520 nm.
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Validation References
PMID 2468669 | |
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PMID 7518447 | |
PMID 19471024 | |
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