PEAR1 Monoclonal / VioBright 515 / REA790

Product Details

Description	Clone REA790 recognizes the human platelet endothelial aggregation receptor 1 (PEAR1) antigen, a type I transmembrane protein also known as MEGF12. PEAR1, an EGF-containing receptor and member of the MEGF family, is found in various tissues. High levels of PEAR1 are found in platelets and endothelial cells, it is weakly expressed in peripheral blood leukocytes and macrophages. PEAR1 becomes activated by platelet contact and is involved in agonist-induced platelet aggregation. \| Additional information: Clone REA790 displays negligible binding to Fc receptors.
Conjugate	VioBright 515
Clone	REA790
Target Species	Human
Applications	FC
Supplier	Miltenyi Biotec
	Catalog #	Sign in to view product details, citations, and spectra
	Size
	Price
	Antigen
	Host
	Isotype

About PEAR1
PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005 [PubMed 15851471]).[supplied by OMIM, Mar 2008]

About VioBright 515
Vio®Bright® B515 from Miltenyi has an excitation peak at 488 nm and an emission peak at 514. It is comparable to BB515 in flow cytometry.

Experiment Design Tools