TCR V beta 11 Monoclonal / VioBlue / REA657

Product Details

Description	Clone REA657 recognizes the mouse V beta 11 T cell receptor (TCR Vbeta11). The T cell receptor (TCR) is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. T cells expressing this receptor are referred to as TCRalpha/beta T cells, though a minority of T cells express an alternate receptor, formed by variable gamma and delta chains, referred as TCRgamma/delta T cells. TCR Vbeta11 is a variant of the TCR beta chain and is expressed on mouse strains with the b haplotype in the TCR beta gene complex, including C57BL/6 and B10, but not on mice strains with the a haplotype, including C57L, SJL, and SWR. \| Additional information: Clone REA657 displays negligible binding to Fc receptors.
Conjugate	VioBlue
Clone	REA657
Target Species	Mouse
Applications	FC
Supplier	Miltenyi Biotec
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About VioBlue
Vio®Blue® has an excitation peak at 400 nm and an emission peak at 455 nm, and is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), V450 (BD Biosciences), Alexa Fluor™ 405 (ThermoFisher), Pacific Blue (ThermoFisher Scientific) and ATTO 425 (AttoTec).

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