MSCA-1 Monoclonal / PE-Vio770 / REA781

Product Details

Description	Clone REA781 recognizes the human mesenchymal stromal cell antigen-1 (MSCA-1) antigen, a GPI-anchored protein also known as tissue non-specific alkaline phosphatase (TNAP). MSCA-1 was shown to be restricted to mesenchymal stromal cells (MSCs) in the CD271bright population in bone marrow. These CD271brightCD45dim MSCs have a much higher clonogenic capacity compared to the CD271+CD45+ fraction in bone marrow. Therefore, MSCA-1 is a suitable marker to identify MSCs with a high proliferative potential. \| Additional information: Clone REA781 displays negligible binding to Fc receptors.
Conjugate	PE-Vio770
Clone	REA781
Target Species	Human
Applications	FC
Supplier	Miltenyi Biotec
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About PE-Vio770
PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.

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