HLA G Monoclonal / PE-Vio770 / 87G

Product Details
Description Clone 87G recognizes the human HLA-G antigen, a heterodimeric class I molecule consisting of a heavy chain and a light chain.The heavy chain is approximately 45 kDa and is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. Clone 87G reacts with isoforms of HLA-G1 and HLA-G5.
Conjugate PE-Vio770
Clone 87G
Target Species Human
Applications FC
Supplier Miltenyi Biotec
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About HLA G
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]
About PE-Vio770
PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.
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