CD205 Monoclonal / PE-Vio615 / REA817

Product Details

Description	Clone REA817 recognizes the mouse CD205 antigen, a 205 kDa integral membrane glycoprotein also known as DEC205 (dendritic and epithelial cells, 205 kDa). This membrane protein acts as an endocytic receptor and thereby mediates efficient processing and presentation of antigens in vivo, leading to the induction of T cell immunity or tolerance. CD205 is expressed at high levels on mouse dendritic cells (DCs) in the skin (Langerhans cells), on DCs residing in the T cell areas of peripheral lymphoid organs, and on DCs generated in vitro from bone marrow progenitors. To a much lower extent, CD205 is also expressed on mature B cells, granulocytes, and T cells. \| Additional information: Clone REA817 displays negligible binding to Fc receptors.
Conjugate	PE-Vio615
Clone	REA817
Target Species	Mouse
Applications	FC
Supplier	Miltenyi Biotec
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About CD205
Predicted to enable signaling receptor activity. Predicted to be involved in immune response and inflammatory response. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

About PE-Vio615
PE-Vio®615 from Miltenyi Biotec has an excitation peak at 565 nm and an emission peak at 619 nm. It is spectrally similar to PE-eFluor™ 610, PE-Dazzle 594 and PE-CF®594

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