Nur77 Monoclonal / PE / REA704
Product Details
Description | Clone REA704 recognizes the mouse Nur77 antigen, a member of the steroid/ thyroid hormone receptor superfamily of intracellular transcription factors. Nur77 is an inducible orphan nuclear receptor also known as NR4A1 or nerve growth factor IB (NGFI-B) and plays a role in cell cycle mediation, inflammation, and apoptosis and is involved in mediation of inflammatory responses in macrophages. Nur77 expression is found on thymocytes and T cell lines and is mainly expressed in testis but also in brain and muscle tissue. | Additional information: Clone REA704 displays negligible binding to Fc receptors. | |
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Conjugate | PE | |
Clone | REA704 | |
Target Species | Mouse | |
Applications | FC | |
Supplier | Miltenyi Biotec | |
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About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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Validation References
PMID 16339277 | |
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PMID 17082578 | |
PMID 18509529 | |
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