Siglec-H Monoclonal / Biotin / REA819
Product Details
| Description | Clone REA819 recognizes the mouse siglec-H antigen, a 34 kDa transmembrane protein of the Ig superfamily known as mouse sialic acid-binding immunoglobulin-like lectin. Siglec-H is specifically expressed on mouse plasmacytoid dendritic cells, a subset of CD11c+ dendritic cells detected at low frequency in all lymphoid tissues, peripheral blood, and some non-lymphoid tissues. Binding of antibodies to siglec-H inhibits type I interferon production, which can be induced in plasmacytoid dendritic cells by DNA and RNA viruses. | Additional information: Clone REA819 displays negligible binding to Fc receptors. | |
|---|---|---|
| Conjugate | Biotin | |
| Clone | REA819 | |
| Target Species | Mouse | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
| Size | ||
| Price | ||
| Antigen | ||
| Host | ||
| Isotype |
Experiment Design Tools
Panel Builders
Looking to design a Microscopy or Flow Cytometry experiment?
Validation References
| PMID 12900525 | |
|---|---|
| PMID 14695235 | |
| PMID 16293595 | |
| Additional Sources |
|
Reviews & Ratings
| Reviews |
|---|
Looking for more options?
135 Siglec-H antibodies from over 10 suppliers available with over 52 conjugates.
