NKp46 Monoclonal / Biotin / REA815

Product Details

Description	Clone REA815 recognizes the mouse CD335 antigen, also known as NKp46, which is a type I transmembrane protein with two extracellular Ig-like domains. It is a member of the natural cytotoxicity receptor (NCR) family, which triggers cytotoxicity in NK cells. NKp46 is involved in target cell recognition and lysis and seems to be exclusively expressed on NK cells. Staining has been shown on BALB/c, SJL, CBA/CA, C57Bl/6, NOD, DBA/2, and B6.129 mice. \| Additional information: Clone REA815 displays negligible binding to Fc receptors.
Conjugate	Biotin
Clone	REA815
Target Species	Mouse
Applications	FC
Supplier	Miltenyi Biotec
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About NKp46
Predicted to be involved in cellular defense response; regulation of natural killer cell mediated cytotoxicity; and signal transduction. Predicted to act upstream of or within defense response to virus and detection of virus. Predicted to be located in cell surface. Predicted to be part of SWI/SNF complex. Predicted to be active in plasma membrane. Biomarker of acquired immunodeficiency syndrome; anogenital venereal wart; hepatitis C; and lymphoproliferative syndrome. [provided by Alliance of Genome Resources, Apr 2022]

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