CD45R (B220) Monoclonal / APC / REA755

Product Details
Description Clone REA755 recognizes the mouse CD45R (B220) antigen, a B lineage-specific surface molecule, which is expressed on B lymphocytes throughout their development from early pro–B stages onwards and is down-regulated upon terminal differentiation to plasma cells. Apart from B cells, CD45R is expressed on a small subset of dendritic cells (plasmacytoid dendritic cells). CD45R is absent in thymus but reported to be present on apoptotic thymocytes. Clone REA755 specifically recognizes the exon A–restricted isoform of mouse CD45. | Additional information: Clone REA755 displays negligible binding to Fc receptors.
Conjugate APC
Clone REA755
Target Species Mouse
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Supplier Miltenyi Biotec
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About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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Validation References
PMID 6984001
PMID 12810165
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