Frizzled-1 Monoclonal / APC / REA603

Product Details
Description Clone REA603 recognizes the mouse frizzled-1 antigen. Frizzled-1 is a member of the frizzled family of proteins which encode seven-transmembrane domain proteins that are receptors for the wingless-type MMTV integration site family of signaling proteins. Frizzled-1 is expressed primarily in the developing lung mesenchyme, in adult heart, placenta, kidney, pancreas, prostate, and ovary. Frizzled-1 interacts with Wnt7b. | Additional information: Clone REA603 displays negligible binding to Fc receptors. |
Conjugate APC
Clone REA603
Target Species Mouse
Applications FC
Supplier Miltenyi Biotec
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About Frizzled-1
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. [provided by RefSeq, Jul 2008]
About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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