RB1 Monoclonal / DyLight 680 / RB1/1754

Product Details
Description Mouse RB1 antibody [DyLight 680] detects Human, Mouse
Conjugate DyLight 680
Clone RB1/1754
Target Species Human, Mouse
Applications IHC-P, WB, IHC
Supplier Novus Biologicals
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About RB1
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
About DyLight 680
DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.
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