CD3 epsilon / DyLight 405 / PC3/188A

Product Details
Description Mouse CD3 epsilon antibody [DyLight 405] detects Human, Rat, Porcine, Bovine, Chicken, Equine, Rabbit
Conjugate DyLight 405
Clone PC3/188A
Target Species Bovine, Chicken, Equine, Human, Porcine, Rabbit, Rat
Applications FC, ICC, IF, IHC-P, WB, IHC
Supplier Novus Biologicals
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About CD3 epsilon
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
About DyLight 405
DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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