CD83 Monoclonal / VioBright FITC / REA714

Product Details
Description Clone REA714 recognizes the human CD83 antigen, a 45 kDa glycoprotein member of the immunoglobulin superfamily of receptors. In humans, CD83 is expressed on the surface of activated dendritic cells (DCs) and can therefore be used as a marker for the phenotypical characterization of DC maturation. CD83 plays a role in antigen presentation and lymphocyte activation. | Additional information: Clone REA714 displays negligible binding to Fc receptors.
Conjugate VioBright FITC
Clone REA714
Target Species Human
Applications FC
Supplier Miltenyi Biotec
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About CD83
The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
About VioBright FITC
Vio®Bright FITC has an excitation peak at 496 nm and an emission peak at 522 nm. It is recommended for use in flow cytometry and fluorescence microscopy.
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