CD228 Monoclonal / APC / REA717
Product Details
| Description | Clone REA717 recognizes the human CD228 antigen, a cell-surface sialoglycoprotein also known as MFI2 or melanotransferrin. CD228 is mainly found in human melanomas, but also in liver, epithelium, and in certain fetal tissues. It plays a role in iron cellular uptake. CD228 is internalized before being recycled back to the cell membrane and is also able to bind zinc. | Additional information: Clone REA717 displays negligible binding to Fc receptors. | |
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| Conjugate | APC | |
| Clone | REA717 | |
| Target Species | Human | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD228
The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants. [provided by RefSeq, Jul 2008]
About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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Validation References
| PMID 1544447 | |
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| PMID 7556058 | |
| PMID 17452986 | |
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