TCR V beta 9 Monoclonal / APC-Vio770 / REA727

Product Details

Description	Clone REA727 recognizes the mouse V beta 9 T cell receptor (TCR Vbeta9). The T cell receptor (TCR) is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. T cells expressing this receptor are referred to as TCRalpha/beta T cells, though a minority of T cells express an alternate receptor, formed by variable gamma and delta chains, referred as TCRgamma/delta T cells. TCR Vbeta9 is a variant of the TCR beta chain and is expressed on mouse strains with the b haplotype (e.g. C57BL/6) in the Tcrb gene complex. The Tcrb-V9 gene locus is deleted in mice having the a (e.g. Balb/c) or c (e.g. SJL, NOD) haplotype. Murine Vbeta9+ cells recognize the Mtv-43, Mtv-44, and exogenous MMTV (SW) Mls-1 superantigens. \| Additional information: Clone REA727 displays negligible binding to Fc receptors.
Conjugate	APC-Vio770
Clone	REA727
Target Species	Mouse
Applications	FC
Supplier	Miltenyi Biotec
	Catalog #	Sign in to view product details, citations, and spectra
	Size
	Price
	Antigen
	Host
	Isotype

About TCR V beta 9
Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]

About APC-Vio770
APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.

Experiment Design Tools