TCR V beta 9 Monoclonal / PE-Vio770 / REA727
Product Details
| Description | Clone REA727 recognizes the mouse V beta 9 T cell receptor (TCR Vbeta9). The T cell receptor (TCR) is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. T cells expressing this receptor are referred to as TCRalpha/beta T cells, though a minority of T cells express an alternate receptor, formed by variable gamma and delta chains, referred as TCRgamma/delta T cells. TCR Vbeta9 is a variant of the TCR beta chain and is expressed on mouse strains with the b haplotype (e.g. C57BL/6) in the Tcrb gene complex. The Tcrb-V9 gene locus is deleted in mice having the a (e.g. Balb/c) or c (e.g. SJL, NOD) haplotype. Murine Vbeta9+ cells recognize the Mtv-43, Mtv-44, and exogenous MMTV (SW) Mls-1 superantigens. | Additional information: Clone REA727 displays negligible binding to Fc receptors. | |
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| Conjugate | PE-Vio770 | |
| Clone | REA727 | |
| Target Species | Mouse | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About TCR V beta 9
Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
About PE-Vio770
PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.
PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.
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Validation References
| PMID 2142477 | |
|---|---|
| PMID 2525171 | |
| PMID 3456168 | |
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Reviews & Ratings
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63 TCR V beta 9 antibodies from over 6 suppliers available with over 27 conjugates.
