TCR V beta 9 Monoclonal / PE / REA727
Product Details
| Description | Clone REA727 recognizes the mouse V beta 9 T cell receptor (TCR Vbeta9). The T cell receptor (TCR) is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. T cells expressing this receptor are referred to as TCRalpha/beta T cells, though a minority of T cells express an alternate receptor, formed by variable gamma and delta chains, referred as TCRgamma/delta T cells. TCR Vbeta9 is a variant of the TCR beta chain and is expressed on mouse strains with the b haplotype (e.g. C57BL/6) in the Tcrb gene complex. The Tcrb-V9 gene locus is deleted in mice having the a (e.g. Balb/c) or c (e.g. SJL, NOD) haplotype. Murine Vbeta9+ cells recognize the Mtv-43, Mtv-44, and exogenous MMTV (SW) Mls-1 superantigens. | Additional information: Clone REA727 displays negligible binding to Fc receptors. | |
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| Conjugate | PE | |
| Clone | REA727 | |
| Target Species | Mouse | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About TCR V beta 9
Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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Validation References
| PMID 2142477 | |
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| PMID 2525171 | |
| PMID 3456168 | |
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