CD200 / Alexa Fluor 405 / OX-102

Product Details
Description NB100-65603 recognizes the rat OX2 (CD200) receptor 1. This antigen is a heavily glycosylated 60-100kD cell surface molecule expressed by cells of the myeloid lineage but not by T or B lymphocytes. This antibody has been shown to block the interaction of OX2 receptor 1 with CD200.
Conjugate Alexa Fluor 405
Clone OX-102
Target Species Rat
Applications FC, WB, IHC-Fr, IHC
Supplier Novus Biologicals
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About CD200
This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
About Alexa Fluor 405
Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to V450 (BD Biosciences), Vio®Blue® (Miltenyi Biotec), Cascade Blue® (ThermoFisher Scientific), Pacific Blue® (ThermoFisher Scientific). Alexa 405 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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