Campylobacter jejuni / FITC / 380/412

Product Details

Description	NB100-62426 is specific for Campylobacter jejuni. Some reactivity has been observed with Penner 4 +/- and with Penner 10. C. jejuni is a curved, rod-shaped gram negative bacterium which is a member of the Campylobacteraceae family. They are motile with a polar unsheathed flagellum that results in a corkscrew like motion. They occur primarily as commensals in humans and domestic animals, particularly in chickens where gut temperatures of 42oC are optimal for growth. C. jejuni are one of the most common causes of human diarrhea in the world. Food poisoning can be severely debilitating, although rarely life-threatening as the disease is self limiting. Campylobacter infections are also associated with postinfectious complications including arthritis, Reiter syndrome and Guillain–Barre´ syndrome.
Conjugate	FITC
Clone	380/412
Target Species	Bacteria
Applications	ELISA
Supplier	Novus Biologicals
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About FITC
Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark.

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