JNK (pT183/pY185) / Unconjugated / E.665.10

Product Details
Description Phospho-JNK1/JNK2 (Thr183, Tyr185) Monoclonal Antibody (E.665.10)
Conjugate Unconjugated
Clone E.665.10
Target Species Hamster, Human, Mouse, Rat, Yeast
Applications FC, WB, IP, ChIP, IHC
Supplier Thermo Fisher Scientific
Catalog # Sign in to view product details, citations, and spectra
Size
Price
Antigen
Host
Isotype
About JNK (pT183/pY185)
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]
Experiment Design Tools
Conjugation Options

Pair this antibody with compatibility secondary antibodies, and conjugation kits and services:

Panel Builders

Looking to design a Microscopy or Flow Cytometry experiment?

Validation References
PMID 25582859
PMID 27364558
Additional
Sources
Reviews & Ratings
Looking for more options?

6 JNK (pT183/pY185) antibodies from over 3 suppliers available with over 3 conjugates.

Supplier Page
 Compare