TCR V beta 7.2 Monoclonal / Biotin / REA677
Product Details
Description | Clone REA677 recognizes the human Vbeta7.2 T cell receptor (TCR Vbeta7.2). The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. It is suggested that T cells expressing TCRs with Vbeta7.2 are protective against a pathogenic immune response in Sjögren's syndrome. TCR Vbeta7.2 is expressed on a subset of alpha/beta T cells. | Additional information: Clone REA677 displays negligible binding to Fc receptors. | | |
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Conjugate | Biotin | |
Clone | REA677 | |
Target Species | Human | |
Applications | FC | |
Supplier | Miltenyi Biotec | |
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Validation References
PMID 7931073 | |
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PMID 8206523 | |
PMID 14730616 | |
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16 TCR V beta 7.2 antibodies from over 2 suppliers available with over 8 conjugates.