CD38 Monoclonal / PE-Vio770 / REA683

Product Details
Description Clone REA683 recognizes the rat CD38 antigen, a 42 kDa single-pass type II membrane protein, which is also known as ADP-ribosyl cyclase 1. CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells such as early hematopoietic precursors as well as leukocytes, astrocytes, and epithelial cells. It is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis. | Additional information: Clone REA683 displays negligible binding to Fc receptors.
Conjugate PE-Vio770
Clone REA683
Target Species Rat
Applications FC
Supplier Miltenyi Biotec
Catalog # Sign in to view product details, citations, and spectra
Size
Price
Antigen
Host
Isotype
About CD38
The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
About PE-Vio770
PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.
Experiment Design Tools
Panel Builders

Looking to design a Microscopy or Flow Cytometry experiment?

Validation References
Reviews & Ratings
Looking for more options?

2287 CD38 antibodies from over 54 suppliers available with over 162 conjugates.

Supplier Page
 Compare