TCR V beta 3 Monoclonal / PE-Vio770 / REA646

Product Details

Description	Clone REA646 recognizes the mouse V beta 3 T cell receptor (TCR Vbeta3). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. The alpha and beta TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vbeta3 is a variant of the TCR beta chain and is expressed on T cells having the a, b, and c haplotype of the TCR beta gene complex. \| Additional information: Clone REA646 displays negligible binding to Fc receptors.
Conjugate	PE-Vio770
Clone	REA646
Target Species	Mouse
Applications	FC
Supplier	Miltenyi Biotec
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About PE-Vio770
PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.

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