TCR V alpha 2 Monoclonal / APC / REA679

Product Details
Description Clone REA679 recognizes the mouse Valpha2 T cell receptor (TCR Valpha2) of mice having the a, b, and c haplotypes. The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. TCR Valpha elements are expressed preferentially in CD4 or CD8 subsets in a manner that is largely independent of the MHC haplotype. It is likely that the Valpha elements interact preferentially with conserved regions of class I or class II molecules. | Additional information: Clone REA679 displays negligible binding to Fc receptors.
Conjugate APC
Clone REA679
Target Species Mouse
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Supplier Miltenyi Biotec
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About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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Validation References
PMID 1716770
PMID 2467936
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154 TCR V alpha 2 antibodies from over 12 suppliers available with over 54 conjugates.

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