TCR V beta 11 Monoclonal / APC-Vio770 / REA657

Product Details

Description	Clone REA657 recognizes the mouse V beta 11 T cell receptor (TCR Vbeta11). The T cell receptor (TCR) is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. T cells expressing this receptor are referred to as TCRalpha/beta T cells, though a minority of T cells express an alternate receptor, formed by variable gamma and delta chains, referred as TCRgamma/delta T cells. TCR Vbeta11 is a variant of the TCR beta chain and is expressed on mouse strains with the b haplotype in the TCR beta gene complex, including C57BL/6 and B10, but not on mice strains with the a haplotype, including C57L, SJL, and SWR. \| Additional information: Clone REA657 displays negligible binding to Fc receptors.
Conjugate	APC-Vio770
Clone	REA657
Target Species	Mouse
Applications	FC
Supplier	Miltenyi Biotec
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About APC-Vio770
APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.

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