TCR V beta 17a Monoclonal / PE / REA647

Product Details

Description	Clone REA647 recognizes the mouse V beta 17a T cell receptor (TCR Vbeta17a). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. The alpha and beta TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vbeta17a is a variant of the TCR beta chain and is expressed on T cells having the a haplotype (eg. C57L, SJL, SWR) of the TCRbeta gene complex. \| Additional information: Clone REA647 displays negligible binding to Fc receptors.
Conjugate	PE
Clone	REA647
Target Species	Mouse
Applications	FC
Supplier	Miltenyi Biotec
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About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

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