KLRG1 / Brilliant Violet 786 / 2F1

Product Details
Description BV786 Hamster Anti-Mouse KLRG1
Conjugate Brilliant Violet 786
Clone 2F1
Target Species Mouse
Applications FC
Supplier BD Biosciences
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About KLRG1
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. [provided by RefSeq, Jun 2016]
About Brilliant Violet 786
Brilliant™ Violet 786 (BV786) is a far-red-emitting tandem fluorophore that can be excited by the 405 nm Violet laser and collected using a 780/60 bandpass filter. BV750 has an excitation peak at 405 nm and an emission peak at 786 nm. Due to its unique Stokes shift, few dyes have identical or near identical excitation and emission spectrums, but the nearest alternatives are Qdot® 800 and SuperBright 780 (ThermoFisher), and Brilliant™ Violet 785 (BioLegend). What's the difference between BV785 and BV786? BV785 is a BioLegend color, while BV786 is a BD Biosciences color, but they exhibit the same spectral properties. This dye exhibits a medium level of brightness and is most often used in flow cytometry. Older instruments may not be set up for a dye with such a large Stokes shift, however BV786 is especially well suited for spectral cytometers or sorters. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dye from Beckman Coulter and StarBright dyes from Bio-Rad.
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