CD11b / PE-Alexa 647 / M1/70.15

Product Details
Description RAT ANTI MOUSE CD11b:RPE-Alexa Fluor® 647
Conjugate PE-Alexa 647
Clone M1/70.15
Target Species Human, Mouse, Rabbit
Applications FC
Supplier Bio-Rad
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About CD11b
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
About PE-Alexa 647
PE-Alexa 647 from Thermo Fisher Scientific has an excitation peak at 565 nm and an emission peak at 668 nm. It is useful for flow cytometry applications. PE-Alexa 647 is an alternative to PE-Cy5.
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