CD4 / PE-Alexa 750 / W3/25

Product Details
Description MOUSE ANTI RAT CD4 (DOMAIN 1):RPE-Alexa Fluor® 750
Conjugate PE-Alexa 750
Clone W3/25
Target Species Rat
Applications FC
Supplier Bio-Rad
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About CD4
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
About PE-Alexa 750
PE-Alexa 750 from Thermo Fisher Scientific has an excitation peak at 565 nm and an emission peak at 775 nm. It is useful for flow cytometry applications. PE-Alexa 750 is an alternative to PE-Cy7.
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