CD71 Monoclonal / APC-Vio770 / REA627
Product Details
| Description | Clone REA627 recognizes the mouse CD71 cell-surface antigen, which is also known as transferrin receptor protein 1 (TfR1), and essential for iron transport into proliferating cells. This homodimer is a single-pass type II membrane protein, which is able to bind one transferrin molecule per 90 kDa subunit. CD71 plays a role in cell proliferation by controlling the supply of iron and is expressed on erythroid precursors, immature proliferating cells, reticulocytes, but is very low expressed on resting leukocytes. | Additional information: Clone REA627 displays negligible binding to Fc receptors. | |
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| Conjugate | APC-Vio770 | |
| Clone | REA627 | |
| Target Species | Mouse | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD71
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
About APC-Vio770
APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.
APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.
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Validation References
| PMID 6319033 | |
|---|---|
| PMID 10192390 | |
| PMID 21847081 | |
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Reviews & Ratings
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