CD126 Monoclonal / Biotin / REA620

Product Details

Description	Clone REA620 recognizes the mouse CD126 antigen, a type I cytokine receptor, also known as interleukin 6 receptor subunit alpha (IL-6Ralpha) or membrane glycoprotein 80 (gp80). CD126 is expressed on activated T and B cells, monocytes, hepatocytes, and plasma cells. It associates with the IL-6 receptor beta chain (CD130 or gp130) resulting in the formation of a functional high affinity IL-6 receptor complex. IL-6 plays essential roles in immune response, acute phase reaction, and hematopoiesis. It is an essential factor for B cell differentiation to antibody-forming cells. Deregulated expression of the IL-6 gene is involved in polyclonal plasma cell abnormalities and oncogenesis of plasma cell neoplasias. IL-6 functions as a potent growth factor for multiple myelomas as well as plasmacytomas. \| Additional information: Clone REA620 displays negligible binding to Fc receptors.
Conjugate	Biotin
Clone	REA620
Target Species	Mouse, Rat
Applications	FC
Supplier	Miltenyi Biotec
	Catalog #	Sign in to view product details, citations, and spectra
	Size
	Price
	Antigen
	Host
	Isotype