CD301a Monoclonal / PE-Vio770 / REA581
Product Details
Description | Clone REA581 recognizes the mouse CD301a antigen, a type II transmembrane glycoprotein also known as macrophage galactose-type C-type lectin-1 (MGL1). CD301 has two genes, CD301a and CD301b, which are highly homologous. In contrast to CD301b, that recognizes N-acetylgalactosamine and galactose, including the O-linked Tn antigen, TF antigen, and core 2, CD301a is highly specific for Lewis X and Lewis A structures. It has been suggested that MGL1 is involved in the clearance of apoptotic cells. CD301a is expressed in alternatively activated macrophages. | Additional information: Clone REA581 displays negligible binding to Fc receptors. | |
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Conjugate | PE-Vio770 | |
Clone | REA581 | |
Target Species | Mouse | |
Applications | FC | |
Supplier | Miltenyi Biotec | |
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About PE-Vio770
PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.
PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.
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Validation References
PMID 15591125 | |
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PMID 16096344 | |
PMID 19162326 | |
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