SHIP1 (pY1022) Monoclonal / APC / REA580
Product Details
| Description | Clone REA580 recognizes the human and mouse SHIP-1 antigen, which is a 145 kDa protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. SHIP-1, also known as enzyme phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1, is expressed on hematopoietic cells, including immature CD34+ cells, the majority of T cells, and a minority of B cells. It has a negative effect on cell growth and therefore loss or modification may have profound effects on hematopoietic cell development. Thus SHIP-1 functions as a negative regulator of myeloid cell proliferation and survival. | Additional information: Clone REA580 displays negligible binding to Fc receptors. | |
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| Conjugate | APC | |
| Clone | REA580 | |
| Target Species | Human, Mouse | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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Validation References
| PMID 8769125 | |
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| PMID 8874179 | |
| PMID 9058707 | |
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26 SHIP1 (pY1022) antibodies from over 7 suppliers available with over 5 conjugates.
