CLEC5A Monoclonal / APC / REA582
Product Details
| Description | Clone REA582 recognizes the mouse myeloid DAP12-associating lectin 1 (MDL-1) antigen, also known as C-type lectin domain family 5 member A (CLEC5A) or C-type lectin superfamily member 5 (CLECSF5). MDL-1 is type II transmembrane protein which contains a charged residue in the transmembrane region that enables it to pair with DAP12. MDL-1 is expressed on myeloid cells. It has been suggested, that MDL-1 plays an important role in immune defense as a result of an innate immunity. | Additional information: Clone REA582 displays negligible binding to Fc receptors. | |
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| Conjugate | APC | |
| Clone | REA582 | |
| Target Species | Mouse | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CLEC5A
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined. [provided by RefSeq, Jul 2008]
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined. [provided by RefSeq, Jul 2008]
About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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Validation References
| PMID 10449773 | |
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| PMID 19074552 | |
| PMID 19251634 | |
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Reviews & Ratings
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