RAE-1 alpha/beta/gamma Monoclonal / APC-Vio770 / REA578

Product Details

Description	Clone REA578 recognizes the Rae-1alpha/beta/gamma antigen, a surface protein and member of GPI-linked (glypiated) proteins which share partial homology with MHC class I molecules. Rae-1alpha/beta/gamma were detected in early mouse embryos, especially in the head region. Rae-1 is also up-regulated on a large variety of tumor cells. Together with H-60, Rae-1 is a ligand for the murine NKG2D receptor and a potent stimulator of innate immunity. The ligand-expressing tumour cells induce potent priming of cytotoxic T cells and sensitization of NK cells in vivo. Clone REA578 does not detect Rae-1delta/epsilon. \| Additional information: Clone REA578 displays negligible binding to Fc receptors.
Conjugate	APC-Vio770
Clone	REA578
Target Species	Mouse
Applications	FC
Supplier	Miltenyi Biotec
	Catalog #	Sign in to view product details, citations, and spectra
	Size
	Price
	Antigen
	Host
	Isotype

About APC-Vio770
APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.

Experiment Design Tools