H60a Monoclonal / PE / REA556
Product Details
Description | Clone REA556 recognizes the mouse H60a antigen, a histocompatibility antigen expressed in BALB but not C57BL/6 mouse strains. H60a is expressed on haematopoietic cells and is also is found on tumor cells that constitutively express H60a at the cell surface. H60a is recognized by H60a-specific CD8+ T cells. H60a also binds natural killer group 2, member D (NKG2D) and can participate in tumor surveillance and cancer immunoediting. H60a is up-regulated by certain stimuli including DNA damage and virus infection. | Additional information: Clone REA556 displays negligible binding to Fc receptors. | |
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Conjugate | PE | |
Clone | REA556 | |
Target Species | Mouse | |
Applications | FC | |
Supplier | Miltenyi Biotec | |
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About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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Validation References
PMID 18394936 | |
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PMID 19081632 | |
PMID 21438873 | |
Additional Sources |
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4 H60a antibodies available with over 2 conjugates.