Embigin Monoclonal / PE / REA501
Product Details
| Description | Clone REA501 recognizes the mouse embigin antigen, a single-pass type I membrane protein, which is also known as teratocarcinoma glycoprotein Gp-70. Embigin is a developmentally expressed protein that is a member of the immunoglobulin superfamily class of cell adhesion molecules (CAMs). It is strongly expressed in mouse embryos between five and nine days of gestation but only weakly in adult organs. Embigin plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, embigin promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting the terminal Schwann cell number or their morphology. | Additional information: Clone REA501 displays negligible binding to Fc receptors. | |
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| Conjugate | PE | |
| Clone | REA501 | |
| Target Species | Mouse | |
| Applications | FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About Embigin
This gene encodes a transmembrane glycoprotein that is a member of the immunoglobulin superfamily. The encoded protein may be involved in cell growth and development by mediating interactions between the cell and extracellular matrix. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Jan 2009]
This gene encodes a transmembrane glycoprotein that is a member of the immunoglobulin superfamily. The encoded protein may be involved in cell growth and development by mediating interactions between the cell and extracellular matrix. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Jan 2009]
About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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Validation References
| PMID 1965893 | |
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| PMID 8432389 | |
| PMID 19164284 | |
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Reviews & Ratings
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