CD44H Monoclonal / APC-Vio770 / REA505

Product Details

Description	Clone REA505 recognizes the rat CD44H antigen, a transmembrane glycoprotein, also known as homing-associated cell adhesion molecule (H-CAM) or phagocytic glycoprotein-1 (Pgp-1). CD44H belongs to the CD44 group, that encompasses several isoforms expressed in a variety of tissues. It is highly expressed on hematopoietic and non-hematopoietic cells. All isoforms are encoded by the same gene on chromosome 11 and are formed by alternative splicing of their mRNA. CD44 isoforms belong to the family of cell adhesion molecules and to the sub-family of the hyaladherins in consideration of their affinity for hyaluronate and their structural homology with the cartilage link protein. The standard form of CD44, CD44H, exhibits a high affinity for hyaluronate, plays a role in the uptake and degradation of this glycosaminoglycan, and participates in cell locomotion in its presence. \| Additional information: Clone REA505 displays negligible binding to Fc receptors.
Conjugate	APC-Vio770
Clone	REA505
Target Species	Rat
Applications	FC
Supplier	Miltenyi Biotec
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About APC-Vio770
APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.

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