Integrin alpha 9 beta 1 Monoclonal / VioBright FITC / REA483
Product Details
| Description | Clone REA483 recognizes the human integrin alpha9beta1 antigen, a single-pass type I membrane protein which is also known as integrin alpha-RLC. Integrins are heterodimeric glycoprotein receptors and exist as non-covalently bound alpha and beta subunits. The integrin alpha9beta1 binds a number of extracellular matrix components like VCAM1, cytotactin, and osteopontin to mediate cell adhesion, migration, and tissue invasion. Although widely expressed in a variety of normal human cells including endothelium, different types of muscle cells, hepatocytes, and in the hematopoietic system, it is also expressed in cancer cells. Expression of integrin alpha9beta1 in human cancers appears to correlate with higher grade tumors. | Additional information: Clone REA483 displays negligible binding to Fc receptors. | |
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| Conjugate | VioBright FITC | |
| Clone | REA483 | |
| Target Species | Human | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About VioBright FITC
Vio®Bright FITC has an excitation peak at 496 nm and an emission peak at 522 nm. It is recommended for use in flow cytometry and fluorescence microscopy.
Vio®Bright FITC has an excitation peak at 496 nm and an emission peak at 522 nm. It is recommended for use in flow cytometry and fluorescence microscopy.
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Validation References
| PMID 22039306 | |
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| PMID 22370635 | |
| PMID 25099519 | |
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Reviews & Ratings
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33 Integrin alpha 9 beta 1 antibodies from over 6 suppliers available with over 13 conjugates.
