CD62L / APC-R700 / MEL-14

Product Details
Description APC-R700 Rat Anti-Mouse CD62L
Conjugate APC-R700
Clone MEL-14
Target Species Mouse
Applications FC
Supplier BD Biosciences
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About CD62L
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
About APC-R700
APC-R700 from BD Biosciences has an excitation peak at 651 nm and an emission peak at 705 nm. It's useful in flow cytometry and is spectrally similar to APC-Cy5.5, APC-Alexa 700, APC-Alexa 680 and Seta-APC-705.
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